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Jannat
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JannatLearner
Asked: October 8, 20232023-10-08T12:04:10+06:00 2023-10-08T12:04:10+06:00In: Science

What about scientist Arthur Kornberg and his discovery?

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What about scientist Arthur Kornberg and his discovery?
arthur kornbergscientist
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    1. Jeion Ahmed Expert
      2023-10-08T12:04:40+06:00Added an answer on October 8, 2023 at 12:04 pm

      Arthur Kornberg, born on March 3, 1918, in Brooklyn, New York, and passing away on October 26, 2007, in Stanford, California, was an American biochemist who won the Nobel Prize in Physiology or Medicine in 1959 for his pioneering work on the synthesis of DNA.

      Here are some key discoveries and contributions associated with Arthur Kornberg:

      DNA Replication (1956-1957): Arthur Kornberg discovered and elucidated the process of DNA replication, demonstrating that DNA can be artificially synthesized in a test tube. He identified the enzyme DNA polymerase, which is responsible for building complementary DNA strands based on an existing DNA template.

      DNA Polymerase: Kornberg’s research led to the identification and isolation of DNA polymerase, an enzyme crucial for DNA replication. His work provided fundamental insights into the mechanics of DNA synthesis and laid the foundation for the field of molecular biology.

      Nobel Prize in Physiology or Medicine (1959): Arthur Kornberg was awarded the Nobel Prize in Physiology or Medicine in 1959 for his discovery of the mechanisms in the biological synthesis of ribonucleic acid (RNA) and deoxyribonucleic acid (DNA). He shared the prize with Severo Ochoa, who also contributed to RNA synthesis.

      Enzymatic Synthesis of RNA: In addition to his work on DNA, Kornberg investigated the enzymatic synthesis of RNA, providing critical insights into the processes by which genetic information is transcribed from DNA to RNA.

      Metabolic Pathways and Biochemistry: Kornberg made significant contributions to understanding various metabolic pathways and the biochemistry of cells. He explored processes such as the synthesis of nucleotides and their role in cell function.

      Later Academic and Research Career: Arthur Kornberg had a long and distinguished academic career, serving as a professor and researcher at various prestigious institutions, including Washington University in St. Louis and Stanford University School of Medicine.

      Arthur Kornberg’s groundbreaking work in DNA replication and enzymatic synthesis significantly advanced our understanding of genetics and molecular biology. His contributions have had a lasting impact on the field and continue to be foundational to modern biological research.

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